Homeobox Protein NANOG

Homeobox Protein NANOG

Identifiers Symbol NANOG External IDs OMIM: 607937 MGI: 1919200 HomoloGene: 78027 GeneCards: NANOG Gene

Gene Ontology
Molecular function • DNA binding
• sequence-specific DNA binding transcription factor activity
• sequence-specific DNA binding
Cellular component • nucleus
• nucleolus
Biological process • endodermal cell fate specification
• transcription, DNA-dependent
• regulation of transcription, DNA-dependent
• cell proliferation
• embryo development
• regulation of gene expression
• cell differentiation
• somatic stem cell maintenance
• regulation of cell differentiation
• positive regulation of transcription from RNA polymerase II promoter
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 79923 71950 Ensembl ENSG00000111704 ENSMUSG00000012396 UniProt Q9H9S0 Q80Z64 RefSeq (mRNA) NM_024865.2 NM_028016.2 RefSeq (protein) NP_079141.2 NP_082292.1 Location (UCSC) Chr 12:
7.94 – 7.95 Mb Chr 6:
122.71 – 122.71 Mb PubMed search

NANOG (pron. nanOg) is a transcription factor critically involved with self-renewal of undifferentiated embryonic stem cells. In humans, this protein is encoded by the NANOG gene.

Read more about Homeobox Protein NANOG:  Structure, Function, Name

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