Disease Associations
HLA B7-DR15-DQ6 was found to have an association with postmenopausal osteoporosis in a Greek population.
DR2 (15 or 16) -DQ6.2 has been found to associate with (idiopathic) narcolepsy-cataplexy Hypocretin ligand deficiency in the brain and cerebrospinal fluid is also link to narcolepsy-cataplexy. DR15-DQ6 also shows an association with factors (including a genetic factor on chromosome 12p12) involved in familial multiple sclerosis DR15-DQ6 is strongly associated with the development of choroidal neovascular lesions in presumed ocular histoplasmosis syndrome.
The DR15-DQ6 haplotype may afford some greater protection against the progression of HIV. However, the haplotype is a risk factor in cervical cancer.
Read more about this topic: HLA B7-DR15-DQ6
Famous quotes containing the words disease and/or associations:
“There is a disease to which plays as well as men become liable with advancing years. In men it is called doting, in plays dating. The more topical the play the more it dates.”
—George Bernard Shaw (1856–1950)
“Writing prejudicial, off-putting reviews is a precise exercise in applied black magic. The reviewer can draw free- floating disagreeable associations to a book by implying that the book is completely unimportant without saying exactly why, and carefully avoiding any clear images that could capture the reader’s full attention.”
—William Burroughs (b. 1914)