HKS can refer to:
- the John F. Kennedy School of Government at Harvard University
- HKS (colour system)
- HKS, Inc., an international architecture firm
- HKS (company), Japanese automotive accessory company
- SIMULIA, previously Hibbitt, Karlsson & Sorensen, Inc., a software company
- Hutniczy KS, a nickname of Ruch Chorzów, a Polish football club
- IATA code for Hawkins Field (airport), Jackson, Mississippi, United States
- ICAO code for CHC Helikopter Service, a Norwegian helicopter operator
- Hrvatski košarkaški savez, the native name for the Croatian Basketball Federation
- Hyvinkää centralhospital, a hospital in the Helsinki University Central Hospital hospital area