Struggle Between Xiongnu and Han China
Traversed by the Northern Silk Road, Western Regions is the Chinese name for the Tarim and Dzungaria regions of what is now northwest China. At the beginning of the Han Dynasty (206 BC - AD 220), the region was subservient to the Xiongnu, a powerful nomadic people based in modern Mongolia. In the 2nd century BC, Han China sent Zhang Qian as an envoy to the states in the region, beginning several decades of struggle between the Xiongnu and Han China over dominance of the region, eventually ending in Chinese success. In 60 BC Han China established the Protectorate of the Western Regions (西域都護府) at Wulei (烏壘; near modern Luntai) to oversee the entire region as far west as the Pamir. This became the first sign of Han Chinese rule in Central Asia, the sovereingty of Han dynasty expanded into Central Asia. Tarim Basin and Indo-European kingdoms was under the control of Han dynasty and was influenced by Han Chinese emperors.
During the usurpation of Wang Mang in China, the dependent states of the protectorate rebelled and returned to Xiongnu domination in AD 13. Over the next century, Han China conducted several expeditions into the region, re-establishing the protectorate from 74-76, 91-107, and from 123 onward. After the fall of the Han Dynasty (220), the protectorate continued to be maintained by Cao Wei (until 265) and the Western Jin Dynasty (from 265 onwards).
Read more about this topic: History Of Xinjiang
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