HISD is an acronym that may refer to:
- Huron Intermediate School District, in Bad Axe, Michigan
- Hale Center Independent School District
- Hallettsville Independent School District
- Hallsburg Independent School District
- Hallsville Independent School District
- Hamilton Independent School District
- Hamlin Independent School District
- Hamshire-Fannett Independent School District
- Happy Independent School District
- Hardin Independent School District
- Hardin-Jefferson Independent School District
- Harlandale Independent School District
- Harleton Independent School District
- Harlingen Consolidated Independent School District
- Harmony Independent School District
- Harper Independent School District
- Harrold Independent School District
- Hart Independent School District
- Hartley Independent School District
- Harts Bluff Independent School District
- Haskell Consolidated Independent School District
- Hawkins Independent School District
- Hawley Independent School District
- Hays Consolidated Independent School District
- Hearne Independent School District
- Hedley Independent School District
- Hemphill Independent School District
- Hempstead Independent School District
- Henderson Independent School District
- Henrietta Independent School District
- Hereford Independent School District
- Hermleigh Independent School District
- Hico Independent School District
- Hidalgo Independent School District
- Higgins Independent School District
- High Island Independent School District
- Highland Independent School District
- Highland Park Independent School District (Dallas County)
- Highland Park Independent School District (Potter County)
- Hillsboro Independent School District
- Hitchcock Independent School District
- Holland Independent School District
- Holliday Independent School District
- Hondo Independent School District
- Honey Grove Independent School District
- Hooks Independent School District
- Houston Independent School District
- Howe Independent School District
- Hubbard Independent School District (Bowie County)
- Hubbard Independent School District (Hill County)
- Huckabay Independent School District
- Hudson Independent School District
- Huffman Independent School District
- Hughes Springs Independent School District
- Hull-Daisetta Independent School District
- Humble Independent School District
- Hunt Independent School District
- Huntington Independent School District
- Huntsville Independent School District
- Hurst-Euless-Bedford Independent School District (Tarrant County, Texas)
- Hutto Independent School District