Hirono can refer to the following:
Places:
- Hirono, Fukushima, Japan
- Hirono, Iwate, Japan
- Hirono Station (Fukushima), a stop on the West Japan Railway's Fukuchiyama Line
- Hirono Station (Hyogo), a stop on the Kobe Electric Railway's Sanda Line
Persons:
- Mazie Hirono, an American politician who is currently a United States Representative and Senator-elect for Hawaii
- Koichi Hirono, a Japanese football (soccer) player
- Tadashi Hirono, a Japanese politician
Fictional characters:
- Hirono Shimizu of Battle Royale