Hightower may refer to:
People with the surname Hightower:
- Chelsie Hightower (born 1989), American ballroom dancer
- Cullen Hightower (1923 - 2008), American author of quips and quotes
- Dont'a Hightower (born 1990), American football player
- George Robert Hightower (fl. early 20th century), American academic, President of the Mississippi Agricultural and Mechanical College
- Hank Hightower (born 1966), American pornographic actor
- Jack English Hightower (born 1926), American politician from Texas; U.S. Representative
- Jim Hightower (born 1943), American activist and commentator
- Keith Hightower (born 1957), American politician; mayor of Shreveport, Louisiana
- Loren Hightower (contemporary), American ballet and musical theater dancer
- Rosella Hightower (born 1920), American ballerina
- Rosetta Hightower, American singer
- Scott Hightower (born 1952), American poet and teacher
- Tim Hightower, (born 1986), American football player
- Yolanda Hightower, American competitor in field hockey at the 1988 Summer Olympics
Fictional characters:
- Moses Hightower, a character in the film and series Police Academy
- Hightower (Transformers), multiple characters in the Transformers universe
- Bob Hightower, played by John Wayne in the 1949 western film 3 Godfathers
- Reverend Gail Hightower, a character in the novel Light in August (1932) by William Faulkner
- Reno Hightower, played by Kurt Russell in The Best of Times (1986)
- Steve Hightower, played by Steve Harvey in his TV series The Steve Harvey Show
- Wes Hightower, in the film Urban Cowboy (1980), portrayed by Scott Glenn
- Sheriff Hightower, in the 1990 film Flashback
Other:
- Hightower Bald, a mountain in the state of Georgia, USA
- Hightower High School, Missouri City, Texas, USA