HHV Capsid Portal Protein - Studies

Studies

Studies by amino acid sequence location
pUL-6 Amino acid range Summary Reference
E121, A618, Q621 Point mutations confer resistance to portal assembly inhibitor WAY-150138 van Zeijl, et al., 2000
198-295 Deletion mutant forms immature B-capsids with no portals Nellissery, et al., 2007
322-416 Deletion mutants form immature B-capsids which do contain portals Nellissery, et al., 2007
409-473
L429, L436 Mutation studies suggest putative leucine zipper required for portal ring formation Nellissery, et al., 2007
R676 Carboxyl (C)-terminal end NCBI Sequence
pUL-26.5 "Scaffolding protein" Amino acid range Summary Reference
143-151 Deletion inhibits UL-6 portal assembly Singer, et al., 2005


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