HGH Controversies - Side-effects of High Doses and Long-term Use

Side-effects of High Doses and Long-term Use

Some of the side effects reportedly seen in previously healthy mature patients after taking high HGH doses include:

  • Edema (retention of fluids) in extremities
  • Arthralgia (joint pain)
  • Carpal tunnel syndrome
  • Hypertension.
  • Diabetes and other glucose metabolism imbalances
  • Gynecomastia (enlargement of male mammary glands)

Chronic use of HGH is not well studied. However, in Europe a study called "SAGhE" was undertaken to study these long-term effects of HGH in children. It found that persons with certain kinds of short stature (idiopathic growth hormone deficiency and idiopathic or gestational short stature) who were treated with recombinant human growth hormone during childhood and who were followed over a long period of time, were at a small increased risk of death when compared to individuals in the general population of France. The FDA issued a Safety Alert reporting this result.

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