HFA may stand for:
- Housing Finance Agencies
- New York State Housing Finance Agency
- Harry Fox Agency
- Henry Ford Academy
- Hume-Fogg High School
- High-fidelity audio, a quality of sound reproduction
- High-functioning autism
- High-functioning alcoholic
- Hydrofluoroalkane, a refrigerant chosen to replace Freon-12.
- Hexafluoroacetone-trihydrate, a colourless gas
- Haifa Airport in Haifa, Israel (IATA Airport code: HFA)
- Holy Family Academy, Angeles City, Philippines. A Catholic educational institution.
- Humphrey Field Analyzer, a tool for examining a patient's visual field, produced by Carl Zeiss Meditec, Inc.