Hexa

HEXA

Identifiers Symbols HEXA; TSD External IDs OMIM: 606869 MGI: 96073 HomoloGene: 20146 ChEMBL: 1250415 GeneCards: HEXA Gene EC number 3.2.1.52

Gene Ontology
Molecular function	• beta-N-acetylhexosaminidase activity • cation binding • protein heterodimerization activity
Cellular component	• membrane • lysosomal lumen
Biological process	• skeletal system development • carbohydrate metabolic process • phospholipid metabolic process • sphingolipid metabolic process • glycosphingolipid metabolic process • ganglioside catabolic process • lysosome organization • sensory perception of sound • adult walking behavior • cell death • lipid storage • sexual reproduction • glycosaminoglycan metabolic process • chondroitin sulfate metabolic process • chondroitin sulfate catabolic process • hyaluronan metabolic process • hyaluronan catabolic process • keratan sulfate metabolic process • keratan sulfate catabolic process • myelination • small molecule metabolic process • cell morphogenesis involved in neuron differentiation • neuromuscular process controlling posture • neuromuscular process controlling balance
Sources: Amigo / QuickGO

Orthologs Species Human Mouse Entrez 3073 15211 Ensembl ENSG00000213614 ENSMUSG00000025232 UniProt P06865 P29416 RefSeq (mRNA) NM_000520 NM_010421 RefSeq (protein) NP_000511 NP_034551 Location (UCSC) Chr 15:
72.64 – 72.67 Mb Chr 9:
59.54 – 59.57 Mb PubMed search

Hexosaminidase A (alpha polypeptide), also known as HEXA, is an enzyme that in humans is encoded by the HEXA gene, located on the 15th chromosome.