Benefit To Persons With Sickle Cell Disease
In persons with sickle cell disease, high levels of fetal hemoglobin as found in a newborn or as found abnormally in persons with hereditary persistence of fetal hemoglobin, the HbF causes the sickle cell disease to be less severe. In essence the HbF inhibits polymerization of HbS. A similar mechanism occurs with persons who have sickle cell trait. Approximately 40% of the hemoglobin is in the HbS form while the rest is in HbA form. The HBA form interferes with HbS polymerization.
Read more about this topic: Hereditary Persistence Of Fetal Hemoglobin
Famous quotes containing the words benefit, persons, cell and/or disease:
“I have never taken any exercise, except sleeping and resting, and I never intend to take any. Exercise is loathsome. And it cannot be any benefit when you are tired; and I was always tired.”
—Mark Twain [Samuel Langhorne Clemens] (1835–1910)
“In our Mechanics’ Fair, there must be not only bridges, ploughs, carpenter’s planes, and baking troughs, but also some few finer instruments,—rain-gauges, thermometers, and telescopes; and in society, besides farmers, sailors, and weavers, there must be a few persons of purer fire kept specially as gauges and meters of character; persons of a fine, detecting instinct, who note the smallest accumulations of wit and feeling in the bystander.”
—Ralph Waldo Emerson (1803–1882)
“each in the cell of himself is almost convinced of his freedom,”
—W.H. (Wystan Hugh)
“Smoking ... is downright dangerous. Most people who smoke will eventually contract a fatal disease and die. But they don’t brag about it, do they? Most people who ski, play professional football or drive race cars, will not die—at least not in the act—and yet they are the ones with the glamorous images, the expensive equipment and the mythic proportions. Why this should be I cannot say, unless it is simply that the average American does not know a daredevil when he sees one.”
—Fran Lebowitz (b. 1950)