Hela can stand for:
- Hela, an ancient name for Sri Lanka
- Hela (people), a name for the Sinhala people of Sri Lanka
- Hela (caste), a Hindu caste found in North India
- Hela Language
- HeLa, cells derived from Henrietta Lacks
- Hela Province, a new province being formed from 4 districts of Southern Highlands Province of Papua New Guinea
- Hela, the German name for Hel, Poland
- SMS Hela, light cruiser of the Imperial German Navy
- Hela (Blake), daughter of Tiriel in a poem by William Blake
- Hel (being), Queen of Hel and daughter of Loki in Norse mythology
- Hela (comics), Asgardian goddess from the Marvel Universe
- Health and Safety/Local Authority Liaison Committee (HELA), liaising between the UK Health and Safety Executive and the Local Government Association and Convention of Scottish Local Authorities