Hayles is a surname, and may refer to:
- Andrew Hayles, American basketball player
- Barry Hayles, English born Jamaican football player
- Brian Hayles, English television and film writer
- John Hayles, Tudor agrarian reformer (more commonly Hales)
- N. Katherine Hayles, American literary critic and theorist
- Rob Hayles, English cyclist
- Eustace Robert Hayles. Australian entrepreneur