GX or Gx may refer to:

  • GX Jupitter-Larsen, an American artist and writer
  • GX Logic Modeler
  • F-Zero GX
  • GX (rocket), a Japanese launch vehicle
  • GX (gaming expo), a non gambling game convention in Toronto, Ontario, Canada
  • Lexus GX, a SUV by Lexus
  • Yu-Gi-Oh! GX
  • Gx or gx, is a digraph in the Esperanto x-system orthography, representing the consonant sound, normally spelled as Ĝ or ĝ in the Esperanto alphabet
  • Germ-X
  • Gerrards Cross, a town in Buckinghamshire, England
  • Pacificair IATA airline designator
  • Global Xpress, a satellite communication system by Inmarsat