GWR is an acronym that can stand for:

  • Great Western Railway (or Great Western Railroad), the name of several different railway operators
  • The Gloucestershire Warwickshire Railway — a heritage railway that has taken the initials of the former Great Western Railway Company
  • Great Whipsnade Railway
  • GWR Group, former commercial radio company: owned radio stations, GWR FM (Bristol & Bath) and GWR FM Wiltshire
  • Guinness World Records
  • The GWR Records label
  • Gravitational Wave Radiation
  • Geographically Weighted Regression A local multivariate regression function weighted on spatial dependence
  • Gateway router