Guth may refer to:
- People
- Charlie Guth (1856–1883), baseball player
- Charles Guth (1876–1948), Pepsi Cola Company president
- Eugene Guth (1905–1990), physicist
- Alfred Guth (1908–1996), Austrian pentathlete
- Paul Guth (1910–1997), French humorist and writer
- Forrest Guth (1921–2009), US Army corporal, Purple Heart recipient
- Alan Guth (1947– ), cosmologist
- Bucky Guth (1947– ), baseball player
- John Guth (1981– ), poker player
- Amy Guth, Chicago radio host and writer
- Larry Guth, mathematician
- Other
- 3419 Guth, an asteroid