The term Gutbuster or Gutbusters may refer to several things

  • Gutbusters (TV series), a 2002 documentary following three competitors in the Nathan's International Hot Dog Eating Contest
  • Gutbusters (weight loss programme) is also the name of an Australian weight loss programme
  • Gutbusters are healing potions found in the Multi-User Dungeon Realms of Despair
  • The Gutbuster (race) is an annual race up Baldwin Street, Dunedin — reputedly the world's steepest street