Grue may refer to:
- Grue (monster), a predator invented by Jack Vance and featured in the Zork series
- Grue and bleen, portmanteau words formed from green and blue, coined by Nelson Goodman to illustrate his "new riddle of induction"
- Grue, a linguistic and translation concept (see Distinguishing blue from green in language)
- Grue, Norway, a municipality
- Crane (bird), a gruiform
- Grue (fanzine), an influential science fiction fanzine published by Dean Grennell
- Grue (Freedom City), an alien race in the role-playing game Mutants and Masterminds
- Isle-aux-Grues, an island in Quebec, Canada
- Grues, Vendée, a commune in France
- Grue (river), a river in north-west Italy