Grob Fragmentation

A Grob fragmentation, named for the Swiss chemist Cyril A. Grob, is an elimination reaction taking place when an electrofuge and nucleofuge are situated in positions 1 and 3 on an aliphatic chain. The reaction product is an electrofugal fragment (carbonium ion, acylium ion), an unsaturated fragment (alkene, alkyne, imine) and a nucleofugal fragment (leaving group such as tosyl, hydroxyl).

Grob fragmentation

Read more about Grob Fragmentation:  History, Reaction Mechanism, Scope