Granule is a generic term used for a small particle or grain. The generic term is employed in a variety of specific contexts.
- Granule (solar physics), visible structures in the photosphere of the Sun arising from activity in the Sun's convective zone
- Granule (cell biology), any of several submicroscopic structures, some with explicable origins, others noted only as cell type-specific features of unknown function
- "Azurophil granule", a structure characteristic of the azurophil eukarytotic cell type
- "Chromaffin granule", a structure characteristic of the chromophil eukaryotic cell type
- Martian spherules, spherical granules of material found on the surface of the planet Mars
- Granule (geology), a specified particle size of 2–4 millimetres (-1–-2 on the φ scale)
- In pharmaceutical terms, a granule is small particles gathered into a larger, permanent aggregate in which the original particles can still be identified
- In the Oracle database, a unit of contiguously allocated virtual memory