The acronym GOF may refer to:
- Gang of Four (disambiguation), a generic title with several meanings
- General Operations Forces, a branch of the Malaysian police
- Gamers Outreach Foundation, a philanthropic, non-profit organization
- Goodness of fit, a description of how well a statistical model fits a set of observations
- Gulf of Finland, the easternmost arm of the Baltic Sea
- Harry Potter and the Goblet of Fire, a 2000 novel by J.K. Rowling
- Grand Orient de France, a Masonic organization in France
- Galaxy on Fire, a video game series developed by Fishlabs for mobile devices
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