Glucose-1,6-bisphosphate synthase is a type of enzyme called a phosphotransferase and is involved in mammalian starch and sucrose metabolism (KEGG, 2.7.1.106). It catalyzes the transfer of a phosphate group from 1,3-bisphosphoglycerate to glucose-1-phosphate, yielding 3-phosphoglycerate and glucose-1,6-bisphosphate.
(image courtesy of the BRENDA enzyme database)
The enzyme requires a divalent metal ion cofactor. Zinc 2+, Magnesium 2+, Manganese 2+, Calcium 2+, Nickel 2+, Copper 2+, Cadmium 2+ are all proven effective cofactors. Additionally, the enzyme appears to function optimally in a pH range from 7.3-8.7 and at a temperature of 25 degrees Celsius.
Read more about Glucose-1,6-bisphosphate Synthase: Metabolic Significance of The Catalyzed Reaction, Regulation of The Enzyme, Enzyme Structure, Relevant Links