Structure
Like the other steroid receptors, the glucocorticoid receptor is modular in structure and contains the following domains (labeled A - F):
- A/B - N-terminal regulatory domain
- C - DNA-binding domain (DBD)
- D - hinge region
- E - ligand-binding domain (LBD)
- F - C-terminal domain
Read more about this topic: Glucocorticoid Receptor
Famous quotes containing the word structure:
“There is no such thing as a language, not if a language is anything like what many philosophers and linguists have supposed. There is therefore no such thing to be learned, mastered, or born with. We must give up the idea of a clearly defined shared structure which language-users acquire and then apply to cases.”
—Donald Davidson (b. 1917)
“Communism is a proposition to structure the world more reasonably, a proposition for changing the world. As such, we have to analyze it and, if we deem it reasonable, act upon it.”
—Friedrich Dürrenmatt (1921–1990)