Ghe or GHE may refer to:
- Ge (Cyrillic), a letter of the Cyrillic script called Ghe in many languages, but He in Ukrainian
- Ghe with upturn, a letter of the Cyrillic script now just called Ghe in Ukrainian
- Gernrode-Harzgerode Railway Company, a former private railway company in Germany
- Glass house effect, the resulting phenomenon brought on by an awareness that one is subject to ubiquitous surveillance
- Guitar Hero Encore: Rocks the 80s, a 2007 music video game
- Southern Ghale language, a Tibeto-Burman language of Nepal; ISO-639-3 code: ghe