In population genetics, genetic load or genetic burden is a measure of the cost of lost alleles due to selection (selectional load) or mutation (mutational load). It is a value in the range, where 0 represents no load. The concept was first formulated in 1937 by JBS Haldane, independently formulated, named and applied to humans in 1950 by H. J. Muller, and elaborated further by Haldane in 1957.
Read more about Genetic Load: Definition, Mathematics
Famous quotes containing the words genetic and/or load:
“What strikes many twin researchers now is not how much identical twins are alike, but rather how different they are, given the same genetic makeup....Multiples don’t walk around in lockstep, talking in unison, thinking identical thoughts. The bond for normal twins, whether they are identical or fraternal, is based on how they, as individuals who are keenly aware of the differences between them, learn to relate to one another.”
—Pamela Patrick Novotny (20th century)
“The only human beings I have thoroughly admired and respected in the world have been those who carried the load of the world with a smile, and who, in the face of anxieties that would have knocked me clean out, never showed a tremor. Such men and women end by owning us, soul and body, and our allegiance can never be shaken. We are only too glad to be owned. Religion is nothing but this.”
—Henry Brooks Adams (1838–1918)