History
Until the 1990s, all nonepithelial tumors of the gastrointestinal tract were called "gastrointestinal stromal tumors" from smooth muscle origin. Histopathologists generally did not distinguish between the types, as this did not affect either therapy or prognosis. Subsequently, CD34, and later CD117 were identified as markers that could distinguish the various types.
Read more about this topic: Gastrointestinal Stromal Tumor
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—Karl Marx (1818–1883)