Gars

Gars

Identifiers Symbols GARS; CMT2D; DSMAV; GlyRS; HMN5; SMAD1 External IDs OMIM: 600287 MGI: 2449057 HomoloGene: 1547 GeneCards: GARS Gene EC number 6.1.1.14

Gene Ontology
Molecular function • glycine-tRNA ligase activity
• ATP binding
• protein dimerization activity
Cellular component • cytoplasm
• mitochondrial matrix
• cytosol
• secretory granule
Biological process • tRNA aminoacylation for protein translation
• glycyl-tRNA aminoacylation
• cell death
• gene expression
• diadenosine tetraphosphate biosynthetic process
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 2617 353172 Ensembl ENSG00000106105 ENSMUSG00000029777 UniProt P41250 Q9CZD3 RefSeq (mRNA) NM_002047.2 NM_180678.3 RefSeq (protein) NP_002038.2 NP_851009.2 Location (UCSC) Chr 7:
30.63 – 30.67 Mb Chr 6:
55.04 – 55.08 Mb PubMed search

Glycine—tRNA ligase also known as glycyl-tRNA synthetase is an enzyme that in humans is encoded by the GARS gene.

Read more about Gars:  Function, Reaction, Interactions, Clinical Relevance

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