Structure
GABABRs are similar in structure to and in the same receptor family with metabotropic glutamate receptors. There are two subtypes of the receptor, GABAB1 and GABAB2, and these appear to assemble as heterodimers in neuronal membranes by linking up by their intracellular C termini.
It is speculated that binding of GABA causes the subunits to swing shut around the agonist like a venus fly trap.
Read more about this topic: GABAB Receptor
Famous quotes containing the word structure:
“The syntactic component of a grammar must specify, for each sentence, a deep structure that determines its semantic interpretation and a surface structure that determines its phonetic interpretation.”
—Noam Chomsky (b. 1928)
“There is no such thing as a language, not if a language is anything like what many philosophers and linguists have supposed. There is therefore no such thing to be learned, mastered, or born with. We must give up the idea of a clearly defined shared structure which language-users acquire and then apply to cases.”
—Donald Davidson (b. 1917)
“For the structure that we raise,
Time is with materials filled;
Our to-days and yesterdays
Are the blocks with which we build.”
—Henry Wadsworth Longfellow (18091882)