Fyn

FYN

Identifiers Symbols FYN; SLK; SYN; p59-FYN External IDs OMIM: 137025 MGI: 95602 HomoloGene: 48068 ChEMBL: 1841 GeneCards: FYN Gene EC number 2.7.10.2

Gene Ontology
Molecular function	• glycoprotein binding • protein tyrosine kinase activity • non-membrane spanning protein tyrosine kinase activity • protein binding • ATP binding • tubulin binding • T cell receptor binding • CD4 receptor binding • CD8 receptor binding • identical protein binding • phosphatidylinositol 3-kinase binding • ion channel binding • metal ion binding • ephrin receptor binding • peptide hormone receptor binding
Cellular component	• nucleus • mitochondrion • endosome • cytosol • plasma membrane
Biological process	• neuron migration • protein phosphorylation • calcium ion transport • intracellular protein kinase cascade • axon guidance • blood coagulation • learning • feeding behavior • regulation of cell shape • negative regulation of gene expression • viral reproduction • peptidyl-tyrosine phosphorylation • virus-host interaction • platelet activation • forebrain development • T cell costimulation • negative regulation of protein catabolic process • response to drug • response to ethanol • protein autophosphorylation • dendrite morphogenesis • regulation of defense response to virus by virus • activated T cell proliferation • T cell receptor signaling pathway • leukocyte migration • detection of mechanical stimulus involved in sensory perception of pain • cellular response to growth factor stimulus • cellular response to peptide hormone stimulus
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 2534 14360 Ensembl ENSG00000010810 ENSMUSG00000019843 UniProt P06241 P39688 RefSeq (mRNA) NM_001242779 NM_001122892 RefSeq (protein) NP_002028 NP_001116364 Location (UCSC) Chr 6:
111.98 – 112.19 Mb Chr 10:
39.37 – 39.57 Mb PubMed search

Proto-oncogene tyrosine-protein kinase Fyn is an enzyme that in humans is encoded by the FYN gene.