The three-letter acronym FRC can have several different meanings:
- Family Records Centre, the main centre for family history research in England and Wales from 1997-2008
- Family Research Council, a Christian non-profit organization
- Fast Response Cutter, a vessel that is part of the United States Coast Guard's Deepwater program
- Fatah - Revolutionary Council, an international terrorist organization, also known as the Abu Nidal Organization
- Federacion de Radioaficionados de Cuba, an amateur radio organization in Cuba
- Federal Radio Commission, a government body that regulated radio use in the United States from 1926-1934
- Fiber-reinforced composite, a composite building material
- Fiber-reinforced concrete, a concrete with fibers as reinforcements
- Field-Reversed Configuration, a type of magnetic fusion energy device
- The Financial Reporting Council, the UK's independent regulator for corporate reporting and governance
- The Finnish Red Cross, a part of International Federation of Red Cross, one of the biggest and well-known NGOs in the world and in the field of humanitarian aid
- FIRST Robotics Competition, an annual contest between high schools with regional events across the USA, Canada, Brazil and Israel
- First Round Capital, an early-stage venture capital firm in the United States
- Fischer Random Chess, a chess variant
- Fixed Roof Coupé, a car body style that mimics a convertible but with a fixed hardtop
- Flame-resistant clothing, wearing apparel for use in situations where there is risk of arc, flash or thermal burns
- Folk Research Centre of Saint Lucia
- Fort Richmond Collegiate, is a Canadian public high school in Winnipeg, Manitoba
- Frame Rate Control, a method of emulation of the missing colors on LCD when the color of a pixel is changed slightly with every frame
- Frater Rosae Crucis, is the title awarded to advanced members of the Rosicrucian Order
- Cajun French, its ISO 639-3 code is 'frc'.
- French Republican Calendar, a calendar used by the French between 1792 and 1805
- Full Rate Codec, a 13 kit/s speech codec commonly used in the GSM network
- Functional Residual Capacity, the volume of air present in the lungs at the end of passive expiration (medicine)
- "F.R.C (Fat Rich Cunts)", a song by The Screaming Jets from their 1991 album All for One
- False Roman Cancel, a technique used in the fighting game series Guilty Gear