Scientific Career
Ernst Neumann made many contributions in the field of hematology. He demonstrated that erythropoiesis and leukopoiesis formulate in the bone marrow. “Ernst Neumann postulated a common stem cell for all hematopoietic cells” (Brittinger, 1995). In 2007, Zech et al. wrote: “The beginning of Stem Cell research can be dated back to Ernst Neumann, who was appointed professor of pathology at Koenigsberg in 1866 and described in a preliminary communication the presence of nucleated red blood cells in bone marrow (BM) saps. He concluded in his subsequent papers, that during postembryonic life, erythropoiesis and leukopoiesis are taking place in the BM. On the basis of his observation, Ernst Neumann was the first to postulate the BM as blood forming organ with a common SC for all hematopoietic cells” (Zech,N.H., Shkumatov, A. Koestenbauer,S., 2007)
"Among his "firsts" were the identification of leukemia and of pernicious anemia as diceases of the marrow. He coined the term myelogeneous leukemia, (today's acute myeloid leukemia), and described in 1882 the law of dissemination concerning yellow and red bone marrow. In effect, he recognized a phenomenon that is sometimes referred to us as Neumann's law. It states that at birth all bones that contain marrow contain red marrow. With age, the blood producing activity contracts toward the center of the body, leaving the more peripheral bones with only fatty marrow. Neumann was supported by Giulio Bizzozero and by Claude Bernard, but there were also Pouchet and Georges Hayem to repudiate him. Despite all the opposition, however, within two decades, Neumann's discovery was a scientific axiom! The brilliance of the truth may first be blinding, but ultimately it supersedes all artificial illuminators" (Tavassoli 1983, p. 62 - 72)
In 1871, Neumann described congenital epulis (CE) of the newborn. Neumann also published an early work on medical electrodiagnosis and formed the name "Hämosiderin" as hematological pigment.
Read more about this topic: Franz Ernst Christian Neumann
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