FPU may stand for:
- Federation of Progressive Unions, a trade union center in Mauritius
- Federation of Trade Unions of Ukraine
- Fishermen's Protective Union, a left populist political party and later service organization in the former Dominion of Newfoundland from 1908 to the 1960s
- Floating-point unit, a part of a computer system specially designed to carry out operations on floating point numbers
- Fresno Pacific University
- Financial Peace University, a training program by Dave Ramsey.
- Filter Paper Unit
- Fermi–Pasta–Ulam problem
- Youth of the Progress Party (Norway) or Fremskrittspartiets Ungdom
- Florida Polytechnic University
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