Major Intersections
| County | Location | Mile | Destination | Notes | |
|---|---|---|---|---|---|
| Levy | Chiefland | 0.00 | US 19 / US 98 / US 27 Alt. / SR 55 |
Western terminus, ALT US 27 joins US 19-98 northbound | |
| Bronson | SR 24 | ||||
| Williston | US 41 / SR 45 / SR 121 | Western end of US 41/SR 121 concurrency | |||
| US 27 / US 41 / SR 45 / SR 121 | Eastern end of US ALT 27/US 41/SR 121 concurrency, Western end of US 27 concurrency | ||||
| Marion | Ocala | I-75 / SR 93 | Exit 354 (I-75) | ||
| US 301 / US 441 / SR 25 / SR 200 | Western end of US 301/441 concurrency | ||||
| SR 40 | |||||
| SR 200 | |||||
| Belleview | US 301 / SR 35 | Eastern end of US 301 concurrency | |||
| Lake | Leesburg | US 27 / SR 25 | Eastern end of US 27 concurrency | ||
| SR 44 | Western end of SR 44 concurrency | ||||
| Silver Lake | CR 44 | Eastern end of SR 44 concurrency | |||
| Tavares | SR 19 | Western end of SR 19 concurrency | |||
| Eustis | SR 19 / CR 19A | Eastern end of SR 19 concurrency | |||
| Mount Dora | SR 46 | ||||
| Orange | Apopka | SR 429 | Exit 33 (SR 429) | ||
| SR 436 | |||||
| Orlando | US 17 / US 92 / SR 50 | Western end of US 17/92 concurrency | |||
| SR 408 | Exit 9 (SR 408) | ||||
| I-4 / SR 400 | Exits 80A-B (I-4) | ||||
| Taft | Turnpike / SR 91 / SR 528 | Exits 254 and 255 (Turnpike), Exit 4 (SR 528/Beachline) | |||
| Osceola | Kissimmee | US 17 / US 92 / US 192 / SR 530 | Western end of US 192(SR 530) concurrency, Eastern End of US 17/92 concurrency | ||
| SR 530 / CR 530 | Eastern end of SR 530 concurrency, County extension of SR 530 | ||||
| Turnpike / SR 91 | Exits 242 NB & 244 SB (Florida's Turnpike) | ||||
| St. Cloud | SR 15 / CR 15 | Northern end of SR 15 concurrency, County extension of SR 15 | |||
| Holopaw | US 441 / SR 15 | Eastern end of US 441 (SR 15) concurrency | |||
| Brevard | June Park | I-95 / SR 9 | Exit 180 (I-95) | ||
| Melbourne | US 1 / SR 5 | ||||
| Indialantic | SR A1A | Eastern terminus | |||
1.000 mi = 1.609 km; 1.000 km = 0.621 mi
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Read more about this topic: Florida State Road 500
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