Farnesyl-diphosphate Farnesyltransferase

Farnesyl-diphosphate farnesyltransferase (FDFT1) (or squalene synthase (SQS)) is an enzyme that converts two units of farnesyl pyrophosphate into squalene.

It has been described as the first dedicated enzyme of sterol (i.e., cholesterol, etc.) synthesis, since the squalene formed by it is exclusively routed into various sterols via a complex, multi-step pathway.

Read more about Farnesyl-diphosphate Farnesyltransferase:  Diversity, Interactive Pathway Map, Clinical Significance