Familial Mediterranean fever (FMF) is a hereditary inflammatory disorder. FMF is an autoinflammatory disease caused by mutations in MEFV, a gene which encodes a 781–amino acid protein denoted pyrin.
The disorder has been given various names including familial paroxysmal polyserositis, periodic peritonitis, recurrent polyserositis, benign paroxysmal peritonitis, periodic disease or periodic fever, Reimann periodic disease or Reimann's syndrome, Siegal-Cattan-Mamou disease, and Wolff periodic disease. Note that "periodic fever" can also refer to any of the Periodic fever syndromes.
Read more about Familial Mediterranean Fever: Epidemiology, Diagnosis, Pathophysiology, Genetics, Treatment, History
Famous quotes containing the word familial:
“That, of course, was the thing about the fifties with all their patina of familial bliss: A lot of the memories were not happy, not mine, not my friends’. That’s probably why the myth so endures, because of the dissonance in our lives between what actually went on at home and what went on up there on those TV screens where we were allegedly seeing ourselves reflected back.”
—Anne Taylor Fleming (20th century)