Enrique is the Spanish variant of Heinrich of Germanic origin. As a given name, it ranked 298 out of 1219 for males of all ages in the 1990 U.S. Census. Equivalents in other languages are Henry (English), Enrico (Italian), Henrik (Swedish, Danish and Norwegian), Henri (French), and Henrique (Portuguese). Common nicknames of Enrique are Kiki, Kiko, Kike or Quique (also spelled Kiké) and Enriqueto or "Enriquito" (meaning "Little Enrique").
Enrique is also a surname and, as a surname, it ranked 32067 out of 88799 for people of all ages in the 1990 U.S. Census. A variant surname is Enriquez (Son of Enrique)
- Enrique of Malacca, slave who may (see article for details) have been the first person to travel around the world
- Enrique Aguirre, athlete
- Enrique Álvarez Félix (1934–1996), Mexican actor
- Enrique Lizalde, Mexican actor
- Enrique Bolaños Geyer, former President of Nicaragua (2002–2007)
- Enrique Bunbury, Spanish singer and band member of Heroes Del Silencio
- Enrique Campos, Venezuelan road bicycle racer
- Enrique-Alfonso Castillo, Australian-Canadian landscape architect
- Enrique Escalante, Puerto Rican volleyball player
- Enrique de la Fuente, Spanish volleyball player
- Enrique Granados, Spanish pianist and classical composer
- Enrique Iglesias, Spanish singer
- Enrique Iglesias (album), his 1995 album
- Enrique (album), his 1999 album
- Enrique Fernando Ortiz Moruno, Spanish football player
- Enrique Martin Morales, Puerto Rican singer better known as Ricky Martin
- Enrique Jardiel Poncela, Spanish playwright
- Jose Enrique, Spanish football player
- Enrique Sabari, Cuban weightlifter
- Quique González, Spanish singer-songwriter
- Quique Sánchez Flores, Spanish football coach
- Enrique Murciano, Cuban-American actor (Without A Trace)
- Jorge Enrique Adoum (1926-2009), Ecuadorian writer