Enolase Superfamily - Members

Members

  • enolase
  • mandelate racemase (MR)
  • muconate lactonizing enzyme (MLE)

The primary sequences of MR and MLE, approximately 25% identical, are related but significantly different; whereas their three-dimensional structures are similar. The enzyme enolase has a more distant, but nevertheless clear, relationship to MLE and MR. The enolase superfamily has served as a model superfamily for understanding enzyme function and is one of the protein families under study by the Enzyme Function Initiative (EFI).

Read more about this topic:  Enolase Superfamily

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