Members
- enolase
- mandelate racemase (MR)
- muconate lactonizing enzyme (MLE)
The primary sequences of MR and MLE, approximately 25% identical, are related but significantly different; whereas their three-dimensional structures are similar. The enzyme enolase has a more distant, but nevertheless clear, relationship to MLE and MR. The enolase superfamily has served as a model superfamily for understanding enzyme function and is one of the protein families under study by the Enzyme Function Initiative (EFI).
Read more about this topic: Enolase Superfamily
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