Emanuele may refer to :
- Carlo Emanuele Buscaglia (1915-1944), Italian aviator,
- Emanuele Basile (died 1980), captain of Carabinieri
- Emanuele Belardi (born 1977), Italian football player
- Emanuele Calaiò (born 1982), Italian football player
- Emanuele Canonica (born 1971), Italian professional golfer
- Emanuele Crialese (born 1965), Italian film screenwriter and director
- Emanuele d'Astorga (1681-1736), Italian composer
- Emanuele Filiberto, 2nd Duke of Aosta (1869-1931), eldest son of Amadeo I of Spain
- Emanuele Filiberto, Prince of Venice and Piedmont (born 1972), member of the House of Savoy
- Emanuele Filippini (born 1973), Italian football defensive midfielder
- Emanuele Idini (born 1970), retired freestyle swimmer
- Emanuele Luzzati (1921-2007), Italian painter, production designer, illustrator, film director and animator
- Emanuele Manitta (born 1977), Italian football goalkeeper
- Emanuele Merisi (born 1972), Italian former professional swimmer
- Emanuele Naspetti (born 1968), racing driver
- Emanuele Nicosia, automobile designer
- Emanuele Nutile (1862-1932), Italian writer and composer
- Emanuele Pesaresi (born 1976), Italian football player
- Emanuele Pesoli (born 1980), Italian football defender
- Emanuele Pirro (born 1962), Italian auto racing driver
- Emanuele Repetti (1776-1852), widely published historian
- Emanuele Severino (born 1929), one of the most important contemporary Italian philosophers
- Vittorio Emanuele, Count of Turin (1872-1946), grandchild of King Victor Emmanuel II
- Vittorio Emanuele, Prince of Naples (born 1937), last Crown Prince of Italy
- Vittorio Emanuele Orlando (1860-1952), Italian diplomat and political figure