ELS may refer to:
- East London Airport, an airport in South Africa that has IATA airport code ELS
- Electrophoretic light scattering, a technique in chemistry
- Encyclopedia of Life Sciences, an encyclopedia of biology
- Engineered Lifting Systems & Equipment Inc, a Canadian Manufacturing Company
- Evangelical Lutheran Synod, a US-based Protestant Christian denomination
- Ejército Libertador del Sur, the Spanish name for the Liberation Army of the South (Mexican Revolution)
- Equidistant letter sequencing, a concept related to bible codes
- l'Ensemble de Lancement Soyouz, the Soyuz-2 (rocket) launch pad at Guiana Space Centre.
- ELS Language Centers, a worldwide network of language schools offering Intensive English Programs
- Extreme Loading for Structures, a structural analysis software
- Lambert-Eaton syndrome, a muscle disease
- Reporting marks for the Escanaba and Lake Superior Railroad
ELS may also refer to:
- Els Límits, a village in the municipality of La Jonquera, Catalonia (Spain)
- Ernie Els (born 1969), South African golfer
In Fiction
- Extraterrestrial Living-metal Shape-shifter a fictional antagonist alien group of the Gundam series Mobile Suit Gundam 00 The Movie: A wakening of the Trailblazer.