Dyrk2

DYRK2

Identifiers Symbols DYRK2; FLJ21217; FLJ21365 External IDs OMIM: 603496 MGI: 1330301 HomoloGene: 48437 ChEMBL: 4376 GeneCards: DYRK2 Gene EC number 2.7.12.1

Gene Ontology
Molecular function	• magnesium ion binding • protein serine/threonine kinase activity • protein serine/threonine/tyrosine kinase activity • protein tyrosine kinase activity • ATP binding • manganese ion binding • ubiquitin binding
Cellular component	• ubiquitin ligase complex • nucleus • nucleolus • cytoplasm • ribonucleoprotein complex • intracellular membrane-bounded organelle
Biological process	• protein phosphorylation • response to DNA damage stimulus • smoothened signaling pathway • intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator • positive regulation of glycogen biosynthetic process • negative regulation of NFAT protein import into nucleus
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 8445 69181 Ensembl ENSG00000127334 ENSMUSG00000028630 UniProt Q92630 Q5U4C9 RefSeq (mRNA) NM_003583 NM_001014390 RefSeq (protein) NP_003574 NP_001014412 Location (UCSC) Chr 12:
68.04 – 68.06 Mb Chr 10:
118.86 – 118.87 Mb PubMed search

Dual specificity tyrosine-phosphorylation-regulated kinase 2 is an enzyme that in humans is encoded by the DYRK2 gene.