Dulcamara means "bittersweet" (literally "sweet-bitter"). It can refer to:
- Solanum dulcamara, a plant
- Dulcamara, a synonym and proposed section of the genus Solanum.
- Dulcamara, or the Little Duck and the Great Quack, a play by W. S. Gilbert
- Dr. Dulcamara, a character in L'elisir d'amore, an opera by Gaetano Donizetti