Ducharme is a surname. Notable people with the surname include:
- Annette Ducharme, Canadian musicisn and songwriter
- Denis Ducharme (1955-), Canadian politician
- Dominique Ducharme (1765–1853), French Canadian settler and fur trader
- Gerry Ducharme (1939-), Canadian politician
- Jean-Marie Ducharme (1723–1807), Fur trader and politician
- Moira Leiper Ducharme, Canadian politician
- Raymond Ducharme Morand (1887–1952), Canadian politician
- Réjean Ducharme (1941-), Canadian novelist and playwright
- Rick Ducharme (1948-), Canadian administrator
- Romulus Ducharme (1886–1976), Canadian politician
- Severin Ducharme (1866-19??), Canadian politician
- Theresa Ducharme (1945–2004), Canadian activist
- Todd Ducharme, Canadian judge
- Debra Ducharme (1954-), Canadian politician, Union Leader and Public Health Care Advocate
- Yves Ducharme (1958-), Canadian politician
| This page or section lists people with the surname Ducharme. If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link. |