Dooley is an Irish surname, and may refer to:
- Bill Dooley (born 1934), American football coach; brother of Vince Dooley
- Billy Dooley, Irish hurling player
- Brian Dooley, British television writer
- Cal Dooley, American politician
- Charlie Dooley, American politician
- Derek Dooley (footballer), British football player and manager
- Derek Dooley (American football) (born 1968), college football coach; son of Vince Dooley and nephew of Bill Dooley
- Dooley Wilson, actor, star of Casablanca
- Edwin B. Dooley, American politician
- James Dooley (disambiguation):
- James Dooley (Australian politician)
- James Dooley (composer), American film score composer
- James H. Dooley, American lawyer
- Jim Dooley, American football player and manager
- John Dooley, physicist
- Kevin Dooley, comics editor
- Paul Dooley, American actor
- Ray Dooley, American actor
- Shaun Dooley, British actor
- Taylor Dooley, American actress
- Thomas Dooley (born 1961), German-American soccer player
- Thomas Anthony Dooley, American physician
- Thomas E. Dooley, American business executive
- Timmy Dooley, Irish politician
- Tom Dooley (editor), American journalist
- Tom Dooley (American football official), American football official
- Vince Dooley (born 1932), American football coach; brother of Bill Dooley and father of Derek Dooley
- Wade Dooley, British rugby player
- Mr. Dooley, a fictional bartender in stories by Finley Peter Dunne