Examples
Drugs belonging to this class are :
- sitagliptin (FDA approved 2006, marketed by Merck & Co. as Januvia),
- vildagliptin (EU approved 2007, marketed in the EU by Novartis as Galvus),
- saxagliptin (FDA approved in 2009, marketed as Onglyza),
- linagliptin (FDA approved in 2011, marketed as Trajenta by Eli Lilly Co and Boehringer Ingelheim),
- dutogliptin (being developed by Phenomix Corporation), Phase III
- gemigliptin (being developed by LG Life Sciences,Korea)
- alogliptin (developed by Takeda Pharmaceutical Company, whose FDA application for the product is currently under review)
Berberine, the common herbal dietary supplement, too inhibits dipeptidyl peptidase-4, which at least partly explains its antihyperglycemic activity.
Read more about this topic: Dipeptidyl Peptidase-4 Inhibitors
Famous quotes containing the word examples:
“It is hardly to be believed how spiritual reflections when mixed with a little physics can hold peoples attention and give them a livelier idea of God than do the often ill-applied examples of his wrath.”
—G.C. (Georg Christoph)
“Histories are more full of examples of the fidelity of dogs than of friends.”
—Alexander Pope (16881744)
“In the examples that I here bring in of what I have [read], heard, done or said, I have refrained from daring to alter even the smallest and most indifferent circumstances. My conscience falsifies not an iota; for my knowledge I cannot answer.”
—Michel de Montaigne (15331592)