Development
The dentate nucleus is highly convoluted, and gyral, or groove, formation is coincident with a critical period of extensive growth in the fetal dentate. The dentate nucleus becomes visible in the cerebellar white matter as early as 11-12 weeks of gestation, containing only smooth lateral and medial surfaces. During this time, the neurons of the dentate nucleus are similar in shape and form, being mainly bipolar cells.
During 22-28 weeks of gestation, which is the critical period in fetal development of the dentate nucleus, gyral formation occurs extensively over the entire surface. Here, neurons mature into various forms of multipolar cells, and the most frequent neuronal types are medium sized to large neurons.
Read more about this topic: Dentate Nucleus
Famous quotes containing the word development:
“Sleep hath its own world,
And a wide realm of wild reality.
And dreams in their development have breath,
And tears, and tortures, and the touch of joy.”
—George Gordon Noel Byron (1788–1824)
“The development of civilization and industry in general has always shown itself so active in the destruction of forests that everything that has been done for their conservation and production is completely insignificant in comparison.”
—Karl Marx (1818–1883)
“Theories of child development and guidelines for parents are not cast in stone. They are constantly changing and adapting to new information and new pressures. There is no “right” way, just as there are no magic incantations that will always painlessly resolve a child’s problems.”
—Lawrence Kutner (20th century)