DEAD Box - Related Families

Related Families

The DEAH and Ski families have had proteins that have been identified to be related to the DEAD box family. These two relatives have a few particularly unique motifs that are conserved within their own family. DEAD box, DEAH, and the Ski families are all referred to as DExD/H proteins. They are all quite distinct from one another and there is not one protein that belongs to more than one of these families. It is thought that each family has a specific role in RNA metabolism, for example both DEAD box and DEAH box proteins NTPase activities become stimulated by RNA, but DEAD box proteins use ATP and DEAH does not.

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