Related Families
The DEAH and Ski families have had proteins that have been identified to be related to the DEAD box family. These two relatives have a few particularly unique motifs that are conserved within their own family. DEAD box, DEAH, and the Ski families are all referred to as DExD/H proteins. They are all quite distinct from one another and there is not one protein that belongs to more than one of these families. It is thought that each family has a specific role in RNA metabolism, for example both DEAD box and DEAH box proteins NTPase activities become stimulated by RNA, but DEAD box proteins use ATP and DEAH does not.
Read more about this topic: DEAD Box
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