CWB may stand for:
- Canadian Western Bank
- Canadian Wheat Board
- Canadian Welding Bureau
- Causeway Bay in Hong Kong
- Center for Wooden Boats, a non-profit organization
- Central Weather Bureau of Taiwan
- Clear Water Bay in Hong Kong
- Computers Without Borders, a non-profit organization
- Conductors Without Borders, an international musical-training effort
- Counterproductive work behavior
- Crunchy Western Boys
- Crazy White Boy
- CWB is the IATA airport code for Afonso Pena International Airport, Brazil
- Cwb is one of three symbols for the Oceanic climate under the Köppen climate classification system, although generally limited to highland areas in the tropics
- The Chocolate Watchband, a psychedelic 60s band