Development
The full-motion videos of Crash Twinsanity were created by Red Eye Studios, who previously created the full-motion videos for Crash Nitro Kart. The soundtrack of Crash Twinsanity was composed, performed, arranged and produced by a cappella band Spiralmouth, while Gabriel Mann recorded and mixed the soundtrack at Asylum Recording Studios in Los Angeles.
Crash Twinsanity marks the debut of Lex Lang as the voice of series antagonist Doctor Neo Cortex. When Lang was called in for an audition to replace previous voice actor Clancy Brown, the voice director described Doctor Cortex to him and had him listen to signature samples of Brown's performance. When Lang was given the freedom to develop the character with the director, they eventually created a depiction of Cortex that was "master evil with a bit of a childish feminine side that leaks out in his tirades" that had everyone laughing at the lines and the character. As a result, that of Cortex stuck. Other voice roles include Mel Winkler as Aku Aku and a tribesman, Michael Ensign as Doctor Nefarious Tropy and a tribesman, Susan Silo as Madame Amberley and Nina Cortex, Debi Derryberry as Coco Bandicoot and Neo Cortex as an eight-year-old, Alex Fernandez as Uka Uka and Farmer Ernest, Dwight Schultz as Dingodile, Rusty Walrus, a tribesman and Papu Papu and Quinton Flynn as Doctor N. Gin, Victor, Moritz and a penguin.
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