Cold agglutinin disease is an autoimmune disease characterized by the presence of high concentrations of circulating antibodies, usually IgM, directed against red blood cells. It is a form of autoimmune hemolytic anemia, specifically one in which antibodies only bind red blood cells at low body temperatures, typically 28-31°C.
It was first described in 1957.
Read more about Cold Agglutinin Disease: Etiology, Pathophysiology, Treatment
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